Research Article
A Novel Risk-Prediction Scoring System for Sepsis among Patients with Acute Pancreatitis: A Retrospective Analysis of a Large Clinical Database
Table 3
Predictive performances and validation of the nomogram.
| Predictive model | AUC | value | NRI | value | IDI | value |
| Training cohort | | | | | | | Nomogram | 0.730 (0.700–0.765) | | | | | | BISAP | 0.632 (0.595–0.673) | <0.001 | 0.548 (0.379–0.736) | <0.001 | 0.118 (0.096–0.141) | <0.001 | SOFA | 0.627 (0.583–0.681) | <0.001 | 0.549 (0.423–0.721) | <0.001 | 0.124 (0.101–0.147) | <0.001 | qSOFA | 0.524 (0.481–0.562) | <0.001 | 0.726 (0.597–0.854) | <0.001 | 0.163 (0.139–0.187) | <0.001 | SIRS | 0.613 (0.573–0.652) | <0.001 | 0.550 (0.393–0.741) | <0.001 | 0.128 (0.102–0.154) | <0.001 |
| Validation cohort | | | | | | | Nomogram | 0.732 (0.680–0.780) | | | | | | BISAP | 0.666 (0.609–0.723) | 0.005 | 0.460 (0.165–0.751) | <0.001 | 0.092 (0.056–0.128) | <0.001 | SOFA | 0.677 (0.595–0.747) | <0.001 | 0.588 (0.375–0.863) | <0.001 | 0.133 (0.098–0.168) | <0.001 | qSOFA | 0.488 (0.421–0.549) | <0.001 | 0.718 (0.552–0.947) | <0.001 | 0.168 (0.131–0.204) | <0.001 | SIRS | 0.614 (0.552–0.673) | <0.001 | 0.592 (0.370–0.865) | <0.001 | 0.136 (0.097–0.175) | <0.001 |
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Abbreviations: AUC, area under the receiver operating characteristic curve; NRI, net reclassification improvement; IDI, integrated discrimination improvement; BISAP, blood urea nitrogen, impaired mental status, systemic inflammatory response syndrome, age and pleural effusion; SOFA, Sequential Organ Failure Assessment; SIRS, systemic inflammatory response syndrome.
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