The Different Effects of Direct Bilirubin on Portopulmonary Hypertension and Idiopathic Pulmonary Arterial Hypertension

Table 4

Independent determinants of PVR elevation from differential laboratory variables in POPH and IPAH.

	Independent predictors	R^2	Standardized β	95% confidence interval	value
POPH	Neutrophils	0.156	0.394	0.109, 0.118	0.030
IPAH	NT-proBNP	0.187	0.433	0.001, 0.002	<0.001

Data were conducted via linear regression analyses. Models were adjusted by gases of blood (continuous variable), metabolic comorbidities (yes or not, categorical variable, including hypertension, diabetes, obesity, and dyslipidaemia), Child-Pugh score (categorical variable), and concomitant medications (categorical variable). PVR, total bilirubin, direct bilirubin, blood cell counts, and NT-proBNP were regarded as continuous variables. PVR, pulmonary vascular resistance; POPH, portopulmonary hypertension; IPAH, idiopathic pulmonary arterial hypertension; NT-proBNP, N-terminal pro brain natriuretic peptide.