Research Article
The Effects of Probiotics and Omega-3 Fatty Acids in Liver Steatosis Induced in Rats by High-Fructose Corn Syrup
Table 5
Glucose, liver enzymes, serum , and triglyceride levels of rats.
| Parameters | Control group (n = 8) | HFCS group (n = 8) | HFCS + omega-3 fatty acids group (n = 8) | HFCS + probiotic group (n = 8) | HFCS + omega-3 fatty acids + probiotic group (n = 8) | | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD |
| Glucose (mg/dL) | 132.98 ± 21.09 | 164.73 ± 15.78a2 | 136.73 ± 15.90b2 | 141.92 ± 21.52b1 | 142.67 ± 24.21b1 | 0.031 | (94.50–155.00) | (149.70–197.40) | (117.50–162.00) | (109.30–175.00) | (110.00–178.00) | | ALT (U/L) | 38.32 ± 7.21 | 67.06 ± 10.42a3 | 33.28 ± 5.09b3 | 28.67 ± 6.54a1.b3 | 37.23 ± 8.52b3.d1 | 0.001 | (29.00–50.80) | (54.80–85.70) | (24.70–41.50) | (21.90–39.80) | (27.20–50.00) | | AST (U/L) | 123.10 ± 68.49 | 169.38 ± 32.30a1 | 118.37 ± 17.34b3 | 97.63 ± 26.89b3 | 121.15 ± 16.36b3 | 0.003 | (81.50–282.50) | (128.50–226.70) | (97.30–152.40) | (68.60–146.90) | (90.60–141.50) | | ALP (U/L) | 96.75 ± 22.95 | 99.12 ± 23.28 | 99.00 ± 18.67 | 90.25 ± 16.85 | 98.50 ± 13.85 | 0.645 | (70.00–138.00) | (54.00–131.00) | (80.00–126.00) | (62.00–119.00) | (71.00–113.00) | | Total cholesterol (mg/dL) | 27.13 ± 5.39 | 40.22 ± 6.43a3 | 32.55 ± 3.94b2 | 33.86 ± 4.09a1.b1 | 29.55 ± 2.49b3 | 0.001 | (19.70–33.90) | (33.60–51.30) | (28.70–40.20) | (29.00–38.90) | (26.10–32.40) | | Triglyceride (mg/dL) | 36.01 ± 13.37 | 60.60 ± 16.73a2 | 40.15 ± 10.84b2 | 44.46 ± 9.87b1 | 42.35 ± 25.87b1 | 0.049 | (18.00–51.70) | (32.00–82.00) | (23.70–62.30) | (26.70–60.60) | (20.70–100.90) | |
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Kruskal–Wallis H-test. Mann–Whitney U test. aFor the control group, ≤ 0.05 a1, ≤ 0.01 a2, ≤ 0.001 a3. bFor the HFCS group, ≤ 0.05 b1, ≤ 0.01 b2, ≤ 0.001 b3. dFor the HFCS + probiotic group, ≤ 0.05 d1, ≤ 0.01 d2, ≤ 0.001 d3. Bold shows statistically significant values. |