Research Article

The Effects of Probiotics and Omega-3 Fatty Acids in Liver Steatosis Induced in Rats by High-Fructose Corn Syrup

Table 5

Glucose, liver enzymes, serum , and triglyceride levels of rats.

ParametersControl group (n = 8)HFCS group (n = 8)HFCS + omega-3 fatty acids group (n = 8)HFCS + probiotic group (n = 8)HFCS + omega-3 fatty acids + probiotic group (n = 8)
Mean ± SDMean ± SDMean ± SDMean ± SDMean ± SD

Glucose (mg/dL)132.98 ± 21.09164.73 ± 15.78a2136.73 ± 15.90b2141.92 ± 21.52b1142.67 ± 24.21b10.031
(94.50–155.00)(149.70–197.40)(117.50–162.00)(109.30–175.00)(110.00–178.00)
ALT (U/L)38.32 ± 7.2167.06 ± 10.42a333.28 ± 5.09b328.67 ± 6.54a1.b337.23 ± 8.52b3.d10.001
(29.00–50.80)(54.80–85.70)(24.70–41.50)(21.90–39.80)(27.20–50.00)
AST (U/L)123.10 ± 68.49169.38 ± 32.30a1118.37 ± 17.34b397.63 ± 26.89b3121.15 ± 16.36b30.003
(81.50–282.50)(128.50–226.70)(97.30–152.40)(68.60–146.90)(90.60–141.50)
ALP (U/L)96.75 ± 22.9599.12 ± 23.2899.00 ± 18.6790.25 ± 16.8598.50 ± 13.850.645
(70.00–138.00)(54.00–131.00)(80.00–126.00)(62.00–119.00)(71.00–113.00)
Total cholesterol (mg/dL)27.13 ± 5.3940.22 ± 6.43a332.55 ± 3.94b233.86 ± 4.09a1.b129.55 ± 2.49b30.001
(19.70–33.90)(33.60–51.30)(28.70–40.20)(29.00–38.90)(26.10–32.40)
Triglyceride (mg/dL)36.01 ± 13.3760.60 ± 16.73a240.15 ± 10.84b244.46 ± 9.87b142.35 ± 25.87b10.049
(18.00–51.70)(32.00–82.00)(23.70–62.30)(26.70–60.60)(20.70–100.90)

Kruskal–Wallis H-test. Mann–Whitney U test. aFor the control group,  ≤ 0.05a1,  ≤ 0.01a2,  ≤ 0.001a3. bFor the HFCS group,  ≤ 0.05b1,  ≤ 0.01b2,  ≤ 0.001b3. dFor the HFCS + probiotic group,  ≤ 0.05d1,  ≤ 0.01d2,  ≤ 0.001d3. Bold shows statistically significant values.