Higher Mean Arterial Pressure during Cardiopulmonary Bypass May Not Prevent Acute Kidney Injury in Elderly Patients Undergoing Cardiac Surgery
Table 4
Subanalysis of risk factors associated with postoperative AKI.
AKI (n = 30)
NO-AKI (n = 62)
value
95% CI
Gender
0.034
Male, n (%)
24 (80.00)
29 (46.77)
Female, n (%)
6 (20.00)
33 (53.23)
Age (year)
70.33 ± 4.69
70.55 ± 4.77
0.839
−2.31to 1.88
BMI (kg/m2)
23.64 ± 2.90
22.89 ± 3.82
0.342
−2.32 to 0.81
Hypertension (n)
13 (43.33%)
25 (40.32%)
0.860
Hemoglobin (g/L)
127.03 ± 16.04
126.40 ± 17.30
0.867
−6.84 to 8.10
Hct (%)
38.30 ± 4.64
38.67 ± 5.02
0.740
−2.53 to 1.80
Preoperative sCr (μmol/L)
84.67 ± 14.97
80.68 ± 16.63
0.269
−3.13 to 11.10
eGFR mL/ (min·1.73 m2)
81.81 ± 15,74
83.60 ± 18.61
0.650
−9.64 to 6.04
Preoperative LVEF (%)
59.73 ± 8.71
59.76 ± 8.04
0.989
−3.68 to 3.63
EuroSCORE II
3.33 ± 1.27
3.69 ± 1.17
0.181
−0.17 to 0.89
Aortic cross-clamp time (min)
106.80 ± 39.43
101.06 ± 42.13
0.534
−12.51 to 23.98
CPB time (min)
154.53 ± 49.44
138.37 ± 52.31
0.161
−6.55 to 38.88
Operation time (min)
302.23 ± 74.76
280.17 ± 100.20
0.288
−18.92 to 63.06
AP (mmHg)
65.68 ± 4.43
64.14 ± 6.80
0.209
−0.86 to 3.88
Delta Hct (%)
−13.57 ± 5.73
−12.07 ± 5.46
0.994
−2.39 to 2.37
Delta sCr (μmol/L)
37.87 ± 17.15
3.09 ± 12.69
<0.001
−41.08 to 28.46
Delta eGFR mL/ (min·1.73 m2)
−28.17 ± 12.72
−1.46 ± 15.79
<0.001
−20.14 to 33.28
Red-cell Transfusions, n
0.304
Yes, n (%)
15 (50)
24 (38.71)
No, n (%)
15 (50)
38 (61.29)
Plasma Transfusions, n
0.133
Yes, n (%)
14 (46.67)
19 (30.65)
No, n (%)
16 (53.33)
43 (69.35)
Extubation time (h)
22.34 ± 17.12
16.11 ± 6.45
0.062
−0.34 to 12.81
Length of ICU (h)
47.27 ± 38.01
32.53 ± 27.16
0.064
−0.88 to 30.36
Postoperative hospital stay (day)
14.27 ± 6.64
12.47 ± 4.52
0.131
−4.14 to 0.55
Percentages are given as total within group; continuous data are presented as mean ± SD; AKI, acute kidney injury; CI, confidence interval; BMI, body mass index; Hct, hematocrit; sCr, serum creatinine; eGFR, estimated glomerular filtration rate; LVEF, left ventricular ejection fraction; CPB, cardiopulmonary bypass; AP, arterial pressure; ICU, intensive care unit.
