Adherence to Lifelines Diet Score (LLDS) Is Associated with a Reduced Risk of Breast Cancer (BrCa): A Case-Control Study
Table 4
Odds ratio (OR) and 95% confidence interval (CI) for breast cancer based on quartiles of food-based Lifelines Diet Score (LLDS).
Quartiles of score
P for trend
Q1
Q2
Q3
Q4
≤31
32–35
36–40
≥41
Overall
Crude model
1.00 (ref)
0.54 (0.30–0.99)
0.45 (0.25–0.79)
0.31 (0.17–0.56)
<0.001
Model 1
1.00 (ref)
0.52 (0.28–0.95)
0.42 (0.23–0.74)
0.28 (0.15–0.52)
<0.001
Model 2†
1.00 (ref)
0.36 (0.18–0.71)
0.37 (0.19–0.70)
0.21 (0.11–0.43)
<0.001
Premenopausal
Crude model
1.00 (ref)
0.78 (0.36–1.67)
0.43 (0.21–0.88)
0.35 (0.16–0.77)
0.003
Model 1
1.00 (ref)
0.93 (0.42–2.04)
0.41(0.19–0.85)
0.38 (0.17–0.85)
0.003
Model 2†
1.00 (ref)
0.51 (0.19–1.30)
0.33 (0.13–0.80)
0.26 (0.10–0.68)
0.003
Postmenopausal
Crude model
1.00 (ref)
0.32 (0.11–0.87)
0.41 (0.16–1.09)
0.23 (0.08–0.63)
0.017
Model 1
1.00 (ref)
0.31 (0.11–0.87)
0.43 (0.16–1.16)
0.22 (0.08–0.63)
0.020
Model 2†
1.00 (ref)
0.30 (0.10–0.94)
0.41 (0.14–1.21)
0.20 (0.06–0.60)
0.015
Binary logistic regression was used to obtain OR and 95% CI. Model 1: adjusted for age and BMI. †Model 2: waist circumference, energy, first pregnancy age, number of children, history of abortion, hormone replacement therapy, use of anti-inflammatory drugs, and vitamin D supplementation.
