Research Article

Association of BIRC5 Gene Polymorphism with the Collateral Circulation and Severity of Large Artery Atherosclerotic Stroke

Table 5

Baseline characteristics of patients grouped by NIHSS scores.

VariablesNIHSS < 6 n = 192NIHSS ≥ 6 n = 236

Age, year (mean ± SD)62.56 ± 10.6464.77 ± 10.480.032
Sex (male) (%)111 (57.81)125 (52.97)0.316
Smoking (%)60 (31.25)92 (38.99)0.096
Drinking (%)64 (33.33)92 (38.99)0.227
Diabetes (%)37 (19.27)54 (22.88)0.364
Hypertension (%)126 (65.62)171 (72.46)0.127
BMI ≥ 25 kg/m2 (%)68 (35.42)78 (33.05)0.608
Total cholesterol (mmol/L) (mean ± SD)4.34 ± 1.144.30 ± 1.290.789
Triglycerides (mmol/L) (mean ± SD)1.65 ± 1.171.62 ± 1.340.808
HDL-C (mmol/L) (mean ± SD)1.11 ± 0.351.03 ± 0.270.012
LDL-C (mmol/L) (mean ± SD)2.78 ± 0.992.84 ± 0.990.535
Homocysteine (mmol/L) (mean ± SD)14.72 ± 8.4716.16 ± 9.860.079
Collateral circulation (good) (%)131 (68.23)47 (19.92)≤0.001
Vascular stenosis (occlusion) (%)118 (61.46)82 (34.75)≤0.001

NIHSS, National Institutes of Health Stroke Survey; SD, standard deviation; BMI, body mass index; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol.