Association of BIRC5 Gene Polymorphism with the Collateral Circulation and Severity of Large Artery Atherosclerotic Stroke

Table 8

Association of BIRC5 SNP of rs2071214 with short-term outcome.

Variables	mRS ≤ 2 n = 176	mRS > 2 n = 252	^a	OR (95% CI)^a
rs 2071214
Additive model
AA	71 (40.34%)	84 (33.33%)		1.00
GA	81 (46.02%)	119 (47.22%)	0.815	1.056 (0.668–1.670)
GG	24 (13.64%)	49 (19.44%)	0.336	1.356 (0.729–2.521)
Dominant model
AA	71 (40.34%)	84 (33.33%)		1.00
GA/GG	105 (59.66%)	168 (66.67%)	0.589	1.126 (0.731–1.736)
Recessive model
AA/GA	152 (86.36%)	203 (80.56%)		1.00
GG	24 (13.64%)	49 (19.44%)	0.342	1.314 (0.748–2.307)

Logistic regression analysis was used to evaluate the distribution of the genotype frequencies of rs2071214 polymorphisms in mRS ≤ 2 and mRS > 2 group. OR, odds ratio; CI, confidence interval; Ref, reference; mRS, modified Rankin Scale. ^aAdjusted for HDL-C, LDL-C, and NIHSS scores.