Research Article

Risk Factors Associated with Mortality in COVID-19 Hospitalized Patients: Data from the Middle East

Table 1

Characteristics, comorbidities, and disease severity in patients with COVID-19 (N  = 1,613).

CharacteristicsOverall sample (N  = 1,613)Survived (N  = 1,004)Deceased (N  = 609) value
No. (%)No. (%)No. (%)

Age, years
 18–40148 (9.2)115 (77.7)33 (22.3)<0.001
 41–65737 (45.7)520 (70.6)217 (29.4)
 >65728 (45.1)369 (50.7)359 (49.3)

Gender
 Female668 (41.4)427 (63.9)241 (36.1)0.264
 Male945 (58.6)577 (61.1)368 (38.9)

Body mass index, (kg/m2)
 Underweight (<18.5)4 (0.2)2 (50.0)2 (50.0)0.221
 Normal (18.5–25)227 (14.1)134 (59.0)93 (41.0)
 Overweight (25–30)554 (34.3)357 (64.4)197 (35.6)
 Obese (>30)669 (41.5)403 (60.2)266 (39.8)
 Unknown159 (9.9)108 (67.9)51 (32.1)

Smoking status
 Current smoker223 (13.8)123 (55.2)100 (44.8)0.009
 Ex-smoker191 (11.8)107 (56.0)84 (44.0)
 Nonsmoker1,199 (74.3)774 (64.6)425 (35.4)

Comorbidities
 Hypertension963 (59.7)558 (57.9)405 (42.1)<0.001
 Diabetes mellitus802 (49.7)467 (58.2)335 (41.8)0.001
 Dyslipidemia86 (5.3)52 (60.5)34 (39.5)0.814
 Ischemic heart disease291 (18.0)156 (53.6)135 (46.4)0.001
 Atrial fibrillation60 (3.7)35 (58.3)25 (41.7)0.616
 Heart failure143 (8.9)70 (49.0)73 (51.0)0.001
 Asthma49 (3.0)31 (63.3)18 (36.7)0.999
 Chronic obstructive pulmonary disease17 (1.1)7 (41.2)10 (58.8)0.121
 Sleep apnea12 (0.7)7 (58.3)5 (41.7)0.999
 Cerebrovascular accident (old stroke)110 (6.8)49 (44.5)61 (55.5)<0.001
 Chronic kidney disease127 (7.9)42 (33.1)85 (66.9)<0.001
 End-stage renal disease32 (2.0)18 (56.3)14 (43.8)0.576
 Chronic liver disease4 (0.2)1 (25.0)3 (75.0)0.307
 Liver cirrhosis2 (0.1)0 (0.0)2 (100.0)0.277
 Rheumatoid arthritis21 (1.3)11 (52.4)10 (47.6)0.476
 History of venous thromboembolism26 (1.6)11 (42.3)15 (57.7)0.056
 Immunocompromised65 (4.0)28 (43.1)37 (56.9)0.002
 Malignancy119 (7.4)54 (45.4)65 (54.6)<0.001
 Hypothyroidism78 (4.8)43 (55.1)35 (44.9)0.227
 Gout74 (4.6)46 (62.2)28 (37.8)0.999

Severity on admission
 Moderate226 (14.0)173 (76.5)53 (23.5)<0.001
 Severe522 (32.4)359 (68.8)163 (31.2)
 Critical865 (53.6)472 (54.6)393 (45.4)