Review Article

Takotsubo Cardiomyopathy and Autoimmune Disorders: A Systematic Scoping Review of Published Cases

Table 3

Clinical presentation of 155 patients with Takotsubo cardiomyopathy associated with an autoimmune disease, n (%).

VariableFrequency (%)

Chief complaint
 Not reported50 (32.3%)
 Dyspnea73 (46.9%)
 Chest pain55 (35.3%)
 Palpitation7 (4.4%)
 Cyanosis2 (1.2%)
 Syncope12 (7.7%)
 Cardiopulmonary arrest4 (2.5%)
Number of chief complaints
 Only one65 (41.9%)
 Two32 (20.4%)
 Three and more8 (5.1%)
Abnormal vital sign
 Not reported73 (47.1%)
 At least one abnormal vital sign82 (52.9%)
 Tachycardia37 (23.6%)
 Bradycardia3 (1.9%)
 Hypertension19 (12.2%)
 Hypotension33 (21%)
 Fever16 (10%)
 Hypothermia4 (2.5%)
Tachypnea17 (10.7%)
 Bradypnea
Abnormal cardiovascular exam
 Not reported134 (86.5%)
 Abnormal exam21 (13.5%)
Abnormal CC, VS, PE
 No abnormality reported29 (18.7%)
 At least one abnormal finding126 (81.3%)