Review Article

Takotsubo Cardiomyopathy and Autoimmune Disorders: A Systematic Scoping Review of Published Cases

Table 5

Echocardiography findings in 155 patients with Takotsubo cardiomyopathy associated with autoimmune disease, n (%).

Male (n = 25)Female (n = 130)Total (n = 155)

First EF (EF1)
 Not reported12 (38%)29 (22.3%)41 (26.5%)
 Reported13 (52%)101 (77.7%)114 (73.5%)
 Reduced EF113 (52%)100 (76.9%)113 (72.9%)
 Normal EF10 (0%)1 (0.8%)1 (0.6%)
 Mean EF1 (%)28.1 ± 10.729.8 ± 929.6 ± 9.2
Recovery EF (EF2)
 Not reported11 (44.0%)34 (26.2%)45 (29%)
 Reported EF214 (56.0%)96 (73.8%)110 (71%)
 Reduced EF20 (0%)7 (5.4%)7 (4.5%)
 Normal EF214 (56.0%)89 (68.5%)103 (66.5%)
 Mean EF2 ± SD (%)63.2 ± 6.658.3 ± 958.9 ± 8.8
EF recovery time
 Not applicable9 (5.7%)26 (20%)35 (22.6%)
 Reported16 (10.1%)104 (80%)120 (77.4%)
 Recovery time in days, median (IQR)36.00 (14.00–82.50)18.50 (8.50–42.00)18.50 (10.00–42)

EF: ejection fraction.