Table of Contents
International Journal of Computational Mathematics
Volume 2014, Article ID 694037, 15 pages
Research Article

Mathematical Modeling of Multienzyme Biosensor System

1Department of Mathematics, Syed Ammal Engineering College, Ramanathapuram, Tamil Nadu 623502, India
2Department of Mathematics, The Madura College, Madurai, Tamil Nadu 625011, India

Received 27 March 2014; Revised 18 August 2014; Accepted 8 September 2014; Published 1 October 2014

Academic Editor: Helen McAneney

Copyright © 2014 SP. Ganesan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A mathematical model of hybrid inhibitor biosensor system is discussed. This model consists of five nonlinear partial differential equations for bisubstrate sensitive amperometric system. Simple and closed form of analytical expressions for concentration of glucose-6-phosphate (substrate), potassium dihydrogen phosphate (inhibitor), oxygen (co-substrate), glucose (product 1), and hydrogen peroxide (product 3) is obtained in terms of rate constant using modified Adomian decomposition method (MADM). In this study, behavior of biokinetic parameters is analyzed using this theoretical result. The obtained analytical results (concentrations) are compared with the numerical results and are found to be in satisfactory agreement.