Review Article

In with the Old, in with the New: The Promiscuity of the Duplication Process Engenders Diverse Pathways for Novel Gene Creation

Table 1

Extant percentage of complete, partial and chimeric duplicates originating from small-scale DNA-mediated duplication events in sequenced genomes, mutation accumulation lines, or natural isolates of model organisms.

Phylogenetic distribution % Gene duplicates from SSD-events Comments References
CompletePartialChimeric

C aenorhabditis elegans
 Sequenced genome of N2 strain392140290 duplicate pairs with 𝑑 𝑆 ≤ 0.10 [76]
 Mutation accumulation (MA) lines376330 spontaneous duplication events across ten MA lines bottlenecked for an average of 432 generations[38]
Drosophila melanogaster
 Sequenced genome41273272 duplicate pairs with >80% sequence identity[24]
 Natural isofemale lines147610928 CNVs across 15 natural isolates[45]
Drosophila pseudoobscura
 Sequenced genome4456101 duplicate pairs derived from DNA-mediated duplication events; >80% sequence identity[77]
Saccharomyces cerevisiae
 Sequenced genome897447 duplicate pairs derived from small-scale duplication events; 𝑑 𝑆 ≤ 0.35[78]