Whole-Genome Profiling of a Novel Mutagenesis Technique Using Proofreading-Deficient DNA Polymerase 𝜹

Table 2

Frequency of drug-resistant mutants in the mutator strains.

Plasmids	Mutation frequency of canavanine resistant (×10^−7)	Fold elevation*
YCplac33	3.70	1
YCplac33/polδMKII	486.7±145.0^#	132

*Fold elevation is relative to empty vector.
^#Mean ± standard deviation of 3 SC plates.