Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes

Table 6

SC proteins of the model organisms with similarities to proteins from the proteomes of Deuterostomia.

Eukaryotic taxa	Total proteins in the NCBI database^a	Proteins of the SC central space		Lateral element proteins and other SC proteins
		1	2	3	4
		From animals	From plants and fungi	From plants and fungi	From animals
Echinodermata (Deuterostomia 1)	41869	SYCE2 Dr (50), SYCE2 Mm (68), SYCP1 Mm (76)c, C(3)G Dm (63),; SYP-1 Ce (59),; SYCE2-like annotated for Strongylocentrotus purpuratus	ZYP1b At (65),; ZYP1a At (74)c	ASY2 At (69),; ASY1 At (125),; Hop1 Sc (75)	FKBP6 Mm (104), SYCP2 Mm (118), SYCP3-like Dr (157), SYCP3 Mm (169), SC65 Dr (176), SC65 Mm (179),; SCP3-like annotated for Strongylocentrotus purpuratus
Hemichordata, Xenoturbellida, and Chaetognatha (Deuterostomia 2)	14118	SYCP1 Mm (69)c, C(3)G Dm (68),; SYP-1 Ce (50)	ZYP1b At (53)c,; ZYP1a At (56)c,; Zip1 Sc (70)	ASY2 At (59),; ASY1 At (121),; Hop1 Sc (85)	FKBP6 Mm (95), SC65 Dr (177),; SC65 Mm (182),; leprecan-like = SC65-like annotated for Saccoglossus kowalevskii
Cephalochordata (Deuterostomia 3)	60054	SYCP1 Dr (69^d), SYCE2 Mm (72), SYCP1 Mm (81^d), C(3)G Dm (59^d)	ZYP1a At (68^d),; ZYP1b At (69)	ASY2 At (50^d),; ASY1 At (87^d),; Hop1 Sc (52^d)	SYCP2 Mm (115), FKBP6 Mm (125), SC65 Dr (127), SC65 Mm (144), SYCP3-like Dr (193),; SYCP3 Mm (194)
Tunicata (Deuterostomia, Chordata)	51435	SYCP1 Dr (55), SYCP1 Mm (57), C(3)G Dm (57)	ZYP1a At (57),; ZYP1b At (66)	Low similarity	SYCP3 Mm (136),; SYCP3-like Dr (140),; SC65 Mm (150),; SC65 Dr (153), FKBP6 Mm (175),; similar to SCP3-like annotated for Ciona intestinalis and leprecan = SC65, for Molgula tectiformis
Actinopterygii (Chordata, Vertebrata, and Teleostomi)	451775	TEX12 Mm (57), SYCE2 Mm (67), SYCE3 Mm (73), SYCE1 Mm (84), SYCP1 Mm (320)b,; C(3)G Dm (59), SYP-1 Ce (50)	ZYP1a At (57),; Zip1 Sc (56)	ASY2 At (70),; ASY1 At (119),; Hop1 Sc (81)	SYCP3 Mm (263), FKBP6 Mm (321), SYCP2 Mm (343), SC65 Mm (471)b,; HIM-3 Ce (73), SC65-like annotated for various fish species
Amphibia (Vertebrata, Teleostomi)	162402	SYCE1-like Dr (50), TEX12 Af (56), TEX12 Mm (72), SYCE2 Mm (84), SYCE1 Mm (93), SYCE3 Mm (110); SYCE1-like, SYCE2-like, TEX12-like annotated for Xenopus tropicalis	Low similarity	ASY2 At (82),; ASY1 At (117)	SYCP2 Dr (50), SYCP3-like Dr (272), SYCP3 Mm (307), FKBP6 Mm (402), SYCP2 Mm (410), SC65 Dr (464), SC65 Mm (523), HIM-3 Ce (63),; SYCP2 and SYCP3 annotated for X. tropicalis, SYCP2-like and SYCP3, for X. laevis; leprecan-like = SC65 precursor, for X. tropicalis, X. laevis
Sauropsida (Vertebrata, Teleostomi)	372873	TEX12 Af (60), SYCE2 Dr (63), SYCE1-like Dr (72), TEX12 Mm (117), SYCE2 Mm (129), SYCE3 Mm (139), SYCE1 Mm (154), SYCP1 Dr (196), SYCP1 Mm (394), C(3)G Dm (52),; SYCP1-like, SYCE1-like, SYCE2-like, SYCE3-like, TEX12-like annotated for various bird species	Zip1 Sc (50)	ASY2 At (90),; ASY1 At (124)	SYCP2 Dr (57), SYCP3-like Dr (275), SYCP3 Mm (346), FKBP6 Mm (387), SC65 Dr (484), SYCP2 Mm (498), SC65 Mm (574),; HIM-3 Ce (74),; SYCP2-like, SCP3, SC65-like annotated for various bird species
Mammalia (Vertebrata, Teleostomi)	2272182	TEX12 Af (64), SYCE2 Dr (68), SYCE1-like Dr (86), SYCP1 Dr (226)b,; SYCP1, SYCE1, SYCE2, SYCE3, TEX12 annotated for various species	Low similarity	ASY2 At (84), ASY1 At (119),; Hop1 Sc (78)	SYCP2 Dr (149),; SYCP3-like Dr (275),; SC65 Dr (489)b, HIM-3 Ce (79),; SYCP2, SYCP3, SC65 annotated for various species

aAs of the time of study start (January-February 2013).
^bSimilarity with cognate proteins is not shown.
^cThese scores (with 𝐸-values ranging from 6𝑒⁻⁰⁷ to 1𝑒⁻¹³) approximate the scores obtained for the random analogs of the SC proteins (𝐸-values ranging from 𝑒⁻⁰⁴ to 4𝑒⁻⁰⁸) (italicized).
^dThe same proteins (different in different cells of the table) from several proteomes under study showed a maximal similarity to the native protein indicated.
Other designations are as in Table 3.