Table of Contents
International Journal of Family Medicine
Volume 2012 (2012), Article ID 649383, 8 pages
http://dx.doi.org/10.1155/2012/649383
Research Article

Retrospective Analysis of Metabolic Syndrome: Prevalence and Distribution in Executive Population in Urban Pakistan

1Department of Family Medicine, Aga Khan University Hospital, Aga Khan University, Stadium Road, P.O. Box 3500, Karachi 74800, Pakistan
2Jinnah Postgraduate Medical College, Jinnah Postgraduate Medical Centre (JPMC), Rafiquee Shaheed Road, P.O. Box 3937, Karachi 74800, Pakistan

Received 30 March 2012; Revised 26 July 2012; Accepted 29 July 2012

Academic Editor: P. Van Royen

Copyright © 2012 Niloufer Sultan Ali et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Kasai, K. Miyauchi, T. Kurata et al., “Prognostic value of the metabolic syndrome for long-term outcomes in patients undergoing percutaneous coronary intervention,” Circulation Journal, vol. 70, no. 12, pp. 1531–1537, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Sundström, U. Risérus, L. Byberg, B. Zethelius, H. Lithell, and L. Lind, “Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study,” BMJ, vol. 332, no. 7546, pp. 878–881, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. A. A. Rizvi, “Inflammation markers as mediators of vasculo-endothelial dysfunction and atherosclerosis in the metabolic syndrome and type 2 diabetes,” Chinese Medical Journal, vol. 120, no. 21, pp. 1918–1924, 2007. View at Google Scholar · View at Scopus
  4. Z. Cao, Y. J. Zhou, Y. X. Zhao, Y. Y. Liu, Y. H. Guo, and W. J. Cheng, “Rosiglitazone could improve clinical outcomes after coronary stent implantation in nondiabetic patients with metabolic syndrome,” Chinese Medical Journal, vol. 119, no. 14, pp. 1171–1175, 2006. View at Google Scholar · View at Scopus
  5. J. B. Buse, H. N. Ginsberg, G. L. Bakris et al., “Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes Association,” Diabetes Care, vol. 30, no. 1, pp. 162–172, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. S. M. Grundy, J. I. Cleeman, S. R. Daniels et al., “Diagnosis and management of the metabolic syndrome An American Heart Association/National Heart, Lung, and Blood Institute scientific statement,” Current Opinion in Cardiology, vol. 21, no. 1, pp. 1–6, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. F. Alsaraj, J. H. McDermott, T. Cawood et al., “Prevalence of the metabolic syndrome in patients with diabetes mellitus,” Irish Journal of Medical Science, vol. 178, no. 3, pp. 309–313, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. B. Balkau, J. E. Deanfield, J. P. Després et al., “International day for the evaluation of abdominal obesity (IDEA): a study of waist circumference, cardiovascular disease, and diabetes mellitus in 168 000 primary care patients in 63 countries,” Circulation, vol. 116, no. 17, pp. 1942–1951, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. Y. W. Park, S. Zhu, L. Palaniappan, S. Heshka, M. R. Carnethon, and S. B. Heymsfield, “The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988–1994,” Archives of Internal Medicine, vol. 163, no. 4, pp. 427–436, 2003. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Gupta, N. Singh, and S. Verma, “South Asians and cardiovascular risk: what clinicians should know,” Circulation, vol. 113, no. 25, pp. e924–e929, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Joshi, S. Islam, P. Pais et al., “Risk factors for early myocardial infarction in South Asians compared with individuals in other countries,” JAMA, vol. 297, no. 3, pp. 286–294, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. W. Rathmann, G. Giani, S. H. Wild et al., “Global prevalence of diabetes: estimates for the year 2000 and projections for 2030,” Diabetes Care, vol. 27, no. 10, pp. 2568–2569, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Nishtar, S. Shera, G. Raffique, K. B. Mohamud, and A. Ahmed, “Diabetes prevention and control: national Action Plan for NCD Prevention, Control and Health Promotion in Pakistan,” Journal of the Pakistan Medical Association, vol. 54, no. 12, pp. S-26–S-30, 2004. View at Google Scholar · View at Scopus
  14. R. L. Hanson, G. Imperatore, P. H. Bennett, and W. C. Knowler, “Components of the “metabolic syndrome” and incidence of type 2 diabetes,” Diabetes, vol. 51, no. 10, pp. 3120–3127, 2002. View at Google Scholar · View at Scopus
  15. P. W. F. Wilson, R. B. D'Agostino, H. Parise, L. Sullivan, and J. B. Meigs, “Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus,” Circulation, vol. 112, no. 20, pp. 3066–3072, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. T. H. Jafar, “Women in Pakistan have a greater burden of clinical cardiovascular risk factors than men,” International Journal of Cardiology, vol. 106, no. 3, pp. 348–354, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. L. Fezeu, B. Balkau, A. P. Kengne, E. Sobngwi, and J. C. Mbanya, “Metabolic syndrome in a sub-Saharan African setting: central obesity may be the key determinant,” Atherosclerosis, vol. 193, no. 1, pp. 70–76, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. V. Tikhonoff and E. Casiglia, “Metabolic syndrome: nothing more than a constellation?” European Heart Journal, vol. 28, no. 7, pp. 780–781, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. R. Kahn, “The metabolic syndrome (Emperor) wears no clothes,” Diabetes Care, vol. 29, no. 7, pp. 1693–1696, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. K. G. M. M. Alberti, P. Zimmet, and J. Shaw, “Metabolic syndrome—a new world-wide definition. A consensus statement from the International Diabetes Federation,” Diabetic Medicine, vol. 23, no. 5, pp. 469–480, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. R. B. Ervin, “Prevalence of metabolic syndrome among adults 20 years of age and over, by sex, age, race and ethnicity, and body mass index: United States, 2003–2006,” National Health Statistics Reports, no. 13, pp. 1–7, 2009. View at Google Scholar · View at Scopus
  22. T. H. Jafar, N. Chaturvedi, and G. Pappas, “Prevalence of overweight and obesity and their association with hypertension and diabetes mellitus in an Indo-Asian population,” CMAJ, vol. 175, no. 9, pp. 1071–1077, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Z. Iqbal Hydrie, A. S. Shera, A. Fawwad, A. Basit, and A. Hussain, “Prevalence of metabolic syndrome in urban Pakistan (Karachi): comparison of newly proposed international diabetes federation and modified adult treatment panel III criteria,” Metabolic Syndrome and Related Disorders, vol. 7, no. 2, pp. 119–124, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Basit and A. S. Shera, “Prevalence of metabolic syndrome in Pakistan,” Metabolic Syndrome and Related Disorders, vol. 6, no. 3, pp. 171–175, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. A. Mohsin, J. Zafar, Y. B. Nisar et al., “Frequency of the metabolic syndrome in adult type2 diabetics presenting to Pakistan Institute of Medical Sciences,” Journal of the Pakistan Medical Association, vol. 57, no. 5, pp. 235–238, 2007. View at Google Scholar · View at Scopus
  26. H. F. Abdul-Rahim, A. Husseini, E. Bjertness, R. Giacaman, N. H. Gordon, and J. Jervell, “The metabolic syndrome in the West Bank population: an urban-rural comparison,” Diabetes Care, vol. 24, no. 2, pp. 275–279, 2001. View at Google Scholar · View at Scopus
  27. G. N. Thomas, S. Y. Ho, E. D. Janus, K. S. L. Lam, A. J. Hedley, and T. H. Lam, “The US National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III) prevalence of the metabolic syndrome in a Chinese population,” Diabetes Research and Clinical Practice, vol. 67, no. 3, pp. 251–257, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. C. Lara-Castro, Y. Fu, B. H. Chung, and W. T. Garvey, “Adiponectin and the metabolic syndrome: mechanisms mediating risk for metabolic and cardiovascular disease,” Current Opinion in Lipidology, vol. 18, no. 3, pp. 263–270, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. O. Renaldi, B. Pramono, H. Sinorita, L. B. Purnomo, R. H. Asdie, and A. H. Asdie, “Hypoadiponectinemia: a risk factor for metabolic syndrome,” Acta Medica Indonesiana, vol. 41, no. 1, pp. 20–24, 2009. View at Google Scholar · View at Scopus
  30. S. A. Isezuo and E. Ezunu, “Demographic and clinical correlates of metabolic syndrome in native African type-2 diabetic patients,” Journal of the National Medical Association, vol. 97, no. 4, pp. 557–563, 2005. View at Google Scholar · View at Scopus
  31. P. Zimmet, G. K. M. M. Alberti, F. Kaufman et al., “The metabolic syndrome in children and adolescents—an IDF consensus report,” Pediatric Diabetes, vol. 8, no. 5, pp. 299–306, 2007. View at Publisher · View at Google Scholar · View at Scopus
  32. C. L. Jennings, E. V. Lambert, M. Collins, Y. Joffe, N. S. Levitt, and J. H. Goedecke, “Determinants of insulin-resistant phenotypes in normal-weight and obese black african women,” Obesity, vol. 16, no. 7, pp. 1602–1609, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. A. M. J. Wassink, Y. Van Der Graaf, S. S. Soedamah-Muthu, W. Spiering, and F. L. J. Visseren, “Metabolic syndrome and incidence of type 2 diabetes in patients with manifest vascular disease,” Diabetes and Vascular Disease Research, vol. 5, no. 2, pp. 114–122, 2008. View at Publisher · View at Google Scholar · View at Scopus
  34. K. G. M. M. Alberti, R. H. Eckel, S. M. Grundy et al., “Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International atherosclerosis society; And international association for the study of obesity,” Circulation, vol. 120, no. 16, pp. 1640–1645, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. S. J. Kim-Dorner, P. A. Deuster, S. A. Zeno, A. T. Remaley, and M. Poth, “Should triglycerides and the triglycerides to high-density lipoprotein cholesterol ratio be used as surrogates for insulin resistance?” Metabolism, vol. 59, no. 2, pp. 299–304, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. A. E. Sumner, K. B. Finley, D. J. Genovese, M. H. Criqui, and R. C. Boston, “Fasting triglyceride and the triglyceride-HDL cholesterol ratio are not markers of insulin resistance in African Americans,” Archives of Internal Medicine, vol. 165, no. 12, pp. 1395–1400, 2005. View at Publisher · View at Google Scholar · View at Scopus
  37. A. E. Sumner, J. Zhou, A. Doumatey et al., “Low HDL-cholesterol with normal triglyceride levels is the most common lipid pattern in West Africans and African Americans with Metabolic Syndrome: implications for cardiovascular disease prevention,” CVD Prevention and Control, vol. 5, no. 3, pp. 75–80, 2010. View at Publisher · View at Google Scholar · View at Scopus
  38. G. Mancia, G. Parati, C. Borghi et al., “Hypertension prevalence, awareness, control and association with metabolic abnormalities in the San Marino population: the SMOOTH study,” Journal of Hypertension, vol. 24, no. 5, pp. 837–843, 2006. View at Publisher · View at Google Scholar · View at Scopus
  39. A. L. Martiniuk, C. M. Lee, C. M. M. Lawes et al., “Hypertension: its prevalence and population-attributable fraction for mortality from cardiovascular disease in the Asia-Pacific region,” Journal of Hypertension, vol. 25, no. 1, pp. 73–79, 2007. View at Publisher · View at Google Scholar · View at Scopus
  40. G. Mancia, M. Bombelli, G. Corrao et al., “Metabolic syndrome in the Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA) study: daily life blood pressure, cardiac damage, and prognosis,” Hypertension, vol. 49, no. 1, pp. 40–47, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. E. Oda, “The metabolic syndrome (emperor) wears no clothes,” Diabetes Care, vol. 29, no. 11, pp. 2566–2567, 2006. View at Publisher · View at Google Scholar · View at Scopus
  42. J. K. Y. Li, M. C. Y. Ng, W. Y. So et al., “Phenotypic and genetic clustering of diabetes and metabolic syndrome in Chinese families with type 2 diabetes mellitus,” Diabetes/Metabolism Research and Reviews, vol. 22, no. 1, pp. 46–52, 2006. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Masoom, I. Pims, and S. Tareen, “Metabolic syndrome in non-diabetic first degree relatives of type 2 diabetic patients,” Annals of Pakistan Institute of Medical Sciences, vol. 7, no. 2, pp. 65–71, 2010. View at Google Scholar
  44. A. Ghosh, T. Liu, M. J. Khoury, and R. Valdez, “Family history of diabetes and prevalence of the metabolic syndrome in U.S. adults without diabetes: 6-year results from the national health and nutrition examination survey (1999-2004),” Public Health Genomics, vol. 13, no. 6, pp. 353–359, 2010. View at Publisher · View at Google Scholar · View at Scopus
  45. M. Das, S. Pal, and A. Ghosh, “Family history of type 2 diabetes and prevalence of metabolic syndrome in adult Asian Indians,” Journal of Cardiovascular Disease Research, vol. 3, no. 2, pp. 104–108, 2012. View at Publisher · View at Google Scholar · View at Scopus
  46. J. Lidfeldt, P. Nyberg, C. Nerbrand, G. Samsioe, B. Scherstén, and C. D. Agardh, “Socio-demographic and psychosocial factors are associated with features of the metabolic syndrome. The Women's Health in the Lund Area (WHILA) study,” Diabetes, Obesity and Metabolism, vol. 5, no. 2, pp. 106–112, 2003. View at Publisher · View at Google Scholar · View at Scopus
  47. M. H. Kim, M. K. Kim, B. Y. Choi, and Y. J. Shin, “Educational disparities in the metabolic syndrome in a rapidly changing society—the case of South Korea,” International Journal of Epidemiology, vol. 34, no. 6, pp. 1266–1273, 2005. View at Publisher · View at Google Scholar · View at Scopus
  48. S. P. Wamala, J. Lynch, M. Horsten, M. A. Mittleman, K. Schenck-Gustafsson, and K. Orth-Gomer, “Education and the metabolic syndrome in women,” Diabetes Care, vol. 22, no. 12, pp. 1999–2003, 1999. View at Google Scholar · View at Scopus
  49. A. K. Khuwaja and M. M. Kadir, “Gender differences and clustering pattern of behavioural risk factors for chronic non-communicable diseases: community-based study from a developing country,” Chronic Illness, vol. 6, no. 3, pp. 163–170, 2010. View at Publisher · View at Google Scholar · View at Scopus