Table of Contents
Research Letters in Inorganic Chemistry
Volume 2009 (2009), Article ID 824561, 4 pages
Research Letter

Synthesis and Characterization of Biologically Active 10-Membered Tetraazamacrocyclic Complexes of Cr(III), Mn(III), and Fe(III)

Department of Chemistry, National Institute of Technology, Kurukshetra 136 119, India

Received 25 January 2009; Accepted 29 March 2009

Academic Editor: Stephen Ralph

Copyright © 2009 Dharam Pal Singh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A new series of macrocyclic complexes of type [M(TML)X] X 2 ; where M = Cr(III), Mn(III), or Fe(III); TML is tetradentate macrocyclic ligand and X = C l 1 , N O 3 1 , C H 3 C O O 1 for Cr(III), Fe(III), and X = C H 3 C O O 1 for Mn(III) has been synthesized by template condensation of succinyldihydrazide and glyoxal. The complexes have been formulated as [M(TML)X] X 2 due to 1:2 electrolytic natures of these complexes as shown by conductivity measurements. The complexes have been characterized with the help of elemental analyses, molar conductance, electronic, infrared, far infrared spectral studies and magnetic susceptibilities. On the basis of these studies, a five-coordinate distorted square-pyramidal geometry, in which two nitrogens and two carbonyl oxygen atoms are suitably placed for coordination toward the metal ion, has been proposed for all the complexes. The complexes were tested for their in vitro antibacterial activity. Some of the complexes showed remarkable antibacterial activities against some selected bacterial strains. The minimum inhibitory concentration shown by these complexes was compared with minimum inhibitory concentration shown by some standard antibiotics like linezolid and cefaclor.