International Journal of Inorganic Chemistry / 2011 / Article / Fig 3

Research Article

Insights into DNA Platination within Unusual Structural Settings

Figure 3

Evolution of the reaction profile for I, cis-[Pt(15NH3)2I2] with the DNA single-strand R,S-d(ATATGsGTATA) containing a single phosphorothioate substitution, recorded as a function of time based on integration of 2D [1H, 15N] HSQC NMR data acquired at a magnetic field strength of 14.1 T (1H = 600 MHz). Key: blue diamond: cis-[Pt(15NH3)2I2] starting material; red square: cis-[Pt(15NH3)2I(OH2)]+ monoaqua, monoiodo adduct; green triangle: cis-[Pt(15NH3)2I,S]+ monoiodo, mono-phosphorothioate adduct; violet circle: cis-[Pt(15NH3)2S,G6-N7]2+ reaction end product.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19.