Research Article

Synthesis, Characterization, and Biological Activity of Some Transition Metal Complexes Derived from Novel Hydrazone Azo Schiff Base Ligand

Table 5

The in vitro antimicrobial activity of ligand, their metal(II) complexes, and free-metal cations evaluated by minimum (MIC inhibitory concentration, μg/mL).

CompoundAntibacterial activityAntifungal activity
Metal complexes (free-metal cations)Metal complexes (free-metal cations)
S. aureusE. coliP. aeruginosaB. subtilisA. nigerC. albicansR. bataicola

CDHBHZ200100350400300200300
[VOL · H2O]75 (175)55 (—)200 (300)150 (—)175 (370)50 (275)200 (250)
[CoL · H2O]10 (350)15 (095)25 (500)20 (410)55 (650)10 (—)75 (—)
[NiL · H2O]30 (215)25 (150)20 (550)80 (—)60 (400)70 (350)35 (450)
[CuL · H2O]10 (400)25 (275)20 (705)15 (550)10 (515)10 (500)30 (655)
[ZnL · H2O]90 (205)45 (—)100 (370)200 (—)50 (—)50 (105)75 (305)
Standard551055105