Table of Contents
International Journal of Inorganic Chemistry
Volume 2013, Article ID 987574, 6 pages
http://dx.doi.org/10.1155/2013/987574
Research Article

Nickel (II) and Iron (II) Complexes with Azole Derivatives: Synthesis, Crystal Structures and Antifungal Activities

1Department of Chemistry, University of Buea, P.O. Box 63, Buea, SWR, Cameroon
2Department of Chemistry, Higher Teachers Training College, University of Bamenda, Bambili, NWR, Cameroon
3Department of Inorganic Chemistry, Coordination Chemistry Laboratory, University of Yaounde I, P.O. Box 812, Yaoundé, Cameroon
4Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan
5Department of Pure and Applied Chemistry, University of Calabar, PMB 1115, Calabar, CRS, Nigeria

Received 15 May 2013; Accepted 8 July 2013

Academic Editor: Alfonso Castiñeiras

Copyright © 2013 Emmanuel N. Nfor et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Two new complexes of nickel (II) with 4-amino-3, 5-bis(pyridyl)-1, 2, 4-triazole (abpt) and iron (II) with 2-(3-phenyl-1H-pyrazole-5-yl) pyridine (phpzpy) have been synthesized and characterized by elemental analysis and IR spectroscopy. The crystal structures of the complexes have been determined by single crystal X-ray diffraction techniques. In the nickel and iron complexes, the ligands are coordinated through nitrogen atoms in bidentate manner. The ligands and their respective complexes have been tested for their antifungal activity against Aspergillus niger, Aspergillus flavus, and Candida albicans. From the study, the complexes showed enhanced activities against the tested organisms compared to the ligands.