Evaluation of a Set of C9 N-acyl Neu5Ac2en Mimetics as Viral Sialidase Selective Inhibitors

Figure 4

Structural overlap of compound 8 (yellow) and DANA (green) in the active site of H1N1 (3B7E). Dotted lines represent the hydrogen bonding. Active site residues interacting with C9 substituent of compound 8 are only indicated for clarity.