International Journal of Medicinal Chemistry / 2012 / Article / Tab 2

Research Article

Syntheses and Biological Activity of Some Derivatives of C-9154 Antibiotic

Table 2

Zones of inhibition (mm) of the analogue and derivatives.

IA/01/1IA/24/1/BIA/21/1/BIA/22/1/BIA/23/1/BIA/19/1/BIA/20/1/BDMSOSparfloxacinFluconazole
(10 μg/mL)(5 μg/mL)(5 μg/mL)(5 μg/mL)(5 μg/mL)(5 μg/mL)(5 μg/mL)(20 μg/mL)(50 μg/mL)

MRSA203229353234310220
S. aureus283032303231320270
S. pyogenes2403037360290240
B. subtilis302632323029310300
C. ulcerans030292730027000
E. coli272729222529270270
P. mirabilis222527272431260220
P. aeruginosa00000000200
S. typhii263027293129220210
S. dysenteriae242727353231240270
K. pneumoniae272427303129270250
C. albicans222224273024210024
A. nigre21000000000
T. rubrum00000000020

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