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International Journal of Medicinal Chemistry
Volume 2012, Article ID 157125, 6 pages
Research Article

Comparative Analysis of the Antioxidant Activity of Cassia fistula Extracts

1Department of Biosciences, Jamia Millia Islamia, New Delhi 110025, India
2School of Chemical Sciences, Central University of Gujarat, Gujarat, Gandhinagar 382030, India
3Department of Medical Education, College of Medicine, King Saud University, Riyadh 11321, Saudi Arabia

Received 24 May 2012; Revised 27 August 2012; Accepted 27 August 2012

Academic Editor: Hussein El-Subbagh

Copyright © 2012 Md. Irshad et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Antioxidant potential of various extracts of Cassia fistula was determined by the DPPH, FRAP, Fe3+ reducing power, and hydrogen peroxide scavenging assay. Methanolic extracts of Cassia fistula showed the highest amount of phenolic and flavonoid content and reducing capacity, whereas hexane extracts exhibited the lowest level of reducing capacity. The order of antioxidant activity in Cassia fistula extracts displayed from higher to lower level as methanolic extracts of pulp, methanolic extracts of seed, hexane extracts of pulp, and hexane extracts of seed. The antioxidant potential of Cassia fistula extracts significantly correlated ( ) with the phenolic content of the methanolic extracts. Ascorbic acid taken as control showed highest antioxidant power in the present study.