Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors

Table 2

Influence of the linker in the 6-acetamidopyridine series on the TrkA potency.

Cpd	L	TrkA^a; % inh. at 30 nM
5	O	96
6		5
7		16
8		6
9		2

^apercentage of inhibition values are reported as the average of ≥3 experiments.