Table 3: Influence of the central phenyl ring substistution in the 6-acetamidopyridine series on the TrkA potency.

412614.tab.003
Cpd TrkAa
% inh. at 30 nM

5HH96
10MeH6
11OMeH15
12HCl0

apercentage of inhibition values are reported as the average of ≥3 experiments.