Table 4: Influence of R1 and R2 substituents on the TrkA potency.

412614.tab.004a
Cpd TrkA
IC50 (nM)

5412614.tab.004bH4
13412614.tab.004cH20
14412614.tab.004dF3
15412614.tab.004eH5
16412614.tab.004fF2
17412614.tab.004gF4

aIC50 values are reported as the average of ≥2 experiments.