International Journal of Medicinal Chemistry / 2012 / Article / Fig 2

Research Article

Pharmacophore Modelling and 3D-QSAR Studies on N πŸ‘ -Phenylpyrazinones as Corticotropin-Releasing Factor 1 Receptor Antagonists

Figure 2

PHASE-generated pharmacophore model AADHHR.47 illustrating hydrogen bond acceptor (A2, A4; pink), hydrogen bond donor (D6; blue), hydrophobic region (H10, H11; green), and aromatic ring (R12; orange) features with distances (in Γ…) between different sites of AADHHR.47.

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