Research Article
Synthesis, Characterization, and Biological Evaluation of Some New Functionalized Terphenyl Derivatives
Table 1
Antibacterial activity of the synthesized compounds: MIC in μg/mL (Zone of inhibition in mm).
| Compound | | | | | (ATTC-25923) | (ATTC-25922) | (ATTC-27853) | (recultured) |
| 3 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | 4 | 12.5 (6) | 12.5 (8) | 12.5 (6) | 12.5 (6) | 5 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (8) | 6 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | 7 | R | 100 (2) | 100 (4) | 100 (5) | 8 | R | R | R | R | 9a | R | R | R | R | 9b | R | R | R | R | 9c | R | R | R | R | 10a | R | R | R | R | 10b | R | R | R | R | 10c | R | R | R | R | 11a | R | R | R | R | 11b | R | R | R | R | 11c | R | R | R | R | 12 | 100 (4) | 6.25 (6) | 6.25 (6) | 6.25 (6) | 13 | R | R | R | R | 14a | R | R | R | R | 14b | R | R | R | R | 14c | R | R | R | R | 15a | R | R | R | R | 15b | R | R | R | R | 15c | R | R | R | R | 16 | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | 17a | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | 17b | R | 12.5 (6) | 12.5 (6) | 12.5 (6) | 17c | 12.5 (6) | 12.5 (6) | 12.5 (6) | 12.5 (6) | 18 | R | R | R | R | 19 | R | R | R | R | Ciprofloxacin | 6.25 (20) | 6.25 (17) | 6.25 (19) | 6.25 (18) |
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Note: R indicates bacterial strains are resistant to the compounds >100 μg/mL.
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