Secondary Structural Preferences of Some Antibacterial Cyclooctapeptides in the Presence of Calcium(II)

Table 2

Antimicrobial susceptibility test results for COP 1–9.

Test peptides		𝐸.𝑐𝑜𝑙𝑖; ATCC 25922; MIC (μg mL^−1)	𝑆.𝑎𝑢𝑟𝑒𝑢𝑠 ATCC 10566; MIC (μg mL^−1)
COP 1	c[Leu-D-Leu-Leu-D-Leu-Lys-D-Lys-Lys-D-Lys]	16	8
COP 2	c[Leu-D-Leu-Leu-D-Trp-Lys-D-Lys-Lys-D-Lys]	16	8
COP 3	c[D-Leu-Leu-D-Leu-Cys-D-Lys-Lys-D-Lys-Lys]	16	16
COP 4	c[D-Leu-Leu-D-Leu-Lys-D-Lys-Lys-D-Lys-Glu]	16	32
COP 5	c[D-Leu-Leu-D-Leu-His-D-Lys-Lys-D-Lys-Glu]	32	128
COP 6	c[D-Leu-Leu-D-Leu-Cys-D-Lys-Lys-D-Lys-Glu]	128	128
COP 7	c[D-Leu-Leu-D-Leu-Leu-D-Lys-Lys-D-Lys-Glu]	>256	>256
COP 8	c[D-Leu-Leu-D-Leu-HIs-D-Lys-His-D-Lys-Glu]	>256	>256
COP 9	c[D-Leu-Leu-D-Leu-Glu-D-Lys-Lys-D-Lys-Glu]	>256	>256