Research Article
Synthesis and Biological Evaluation of Achiral Indole-Substituted Titanocene Dichloride Derivatives
Table 1
Cytotoxicities of titanocenes 5a–5f on CAKI-1 cells using DMSO-, medium-, and soluphor P-based formulations.
| | Compound | IC50 [μM]
(DMSO) | IC50 [μM]
(pure medium) | IC50 [μM]
(soluphor P) |
| | 5a | 10 (±2) | 38 (±3) | 20 (±2) | | 5b | 21 (±3) | 75 (±5) | 27 (±3) | | 5c | 29 (±4) | 13 (±2) | 23 (±1) | | 5d | 140 (±6) | Not measured | Not measured | | 5e | 450 (±10) | Not measured | Not measured | | 5f | >500 | Not measured | Not measured |
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