International Journal of Medicinal Chemistry / 2012 / Article / Tab 1

Research Article

Synthesis and Biological Evaluation of Achiral Indole-Substituted Titanocene Dichloride Derivatives

Table 1

Cytotoxicities of titanocenes 5a5f on CAKI-1 cells using DMSO-, medium-, and soluphor P-based formulations.

CompoundIC50 [μM]
(DMSO)
IC50 [μM]
(pure medium)
IC50 [μM]
(soluphor P)

5a10 (±2)38 (±3)20 (±2)
5b21 (±3)75 (±5)27 (±3)
5c29 (±4)13 (±2)23 (±1)
5d140 (±6)Not measuredNot measured
5e450 (±10)Not measuredNot measured
5f>500Not measuredNot measured

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