Research Article

Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines

Scheme 4

Synthesis of substituted-N,N-bis(benzyl carbamothioyl)-dihydroxy-iso and tetra phthalamides 20a, c, and 21. Reaction conditions: (i) Ph3P(SCN)2 in CH2Cl2 and (ii) NaHCO3, PhCH2NH2.
436397.sch.004