International Journal of Medicinal Chemistry / 2013 / Article / Sch 4

Research Article

Synthesis Characterization and Antibacterial, Antifungal Activity of N-(Benzyl Carbamoyl or Carbamothioyl)-2-hydroxy Substituted Benzamide and 2-Benzyl Amino-Substituted Benzoxazines

Scheme 4

Synthesis of substituted-N,N-bis(benzyl carbamothioyl)-dihydroxy-iso and tetra phthalamides 20a, c, and 21. Reaction conditions: (i) Ph3P(SCN)2 in CH2Cl2 and (ii) NaHCO3, PhCH2NH2.

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