Research Article
Synthesis and Evaluation of Some Novel Chromone Based Dithiazoles as Antimicrobial Agents
Table 2
MIC (μg/mL) of compounds (3a–j) against different bacterial strains.
| | Comp. no. | B. subtilis | S. aureus | E. coli | P. aeruginosa | S. typhi |
| | 3a | 25 | 6.25 | 50 | — | 25 | | 3b | 12.5 | 50 | — | — | — | | 3c | 0.78 | 6.25 | 3.12 | 25 | 12.5 | | 3d | 6.25 | 25 | 12.5 | 50 | — | | 3e | 25 | 6.25 | 25 | — | — | | 3f | 3.12 | 12.5 | 6.25 | 25 | 25 | | 3g | 50 | 3.12 | 3.12 | 12.5 | 50 | | 3h | 1.56 | 12.5 | 1.56 | 6.25 | 25 | | 3i | 25 | 25 | 6.25 | — | — | | 3j | 25 | 25 | — | — | 50 | | Amoxicillin | 0.5 | 0.5 | 0.12 | 1.0 | 0.9 | | Gentamycin | 0.75 | 1.2 | 0.9 | 1.8 | 3.2 |
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