Table of Contents Author Guidelines Submit a Manuscript
International Journal of Medicinal Chemistry
Volume 2014, Article ID 352626, 5 pages
http://dx.doi.org/10.1155/2014/352626
Research Article

Synthesis Antimicrobial and Anticancer Evaluation of 1-Aryl-5-(o-methoxyphenyl)-2-S-benzyl Isothiobiurets

1P.G. Department of Chemistry, Shri Shivaji College, Akola, Maharashtra 444001, India
2P.G. Department of Microbiology, Shri Shivaji College, Akola, Maharashtra 444001, India

Received 15 August 2014; Revised 15 October 2014; Accepted 5 November 2014; Published 20 November 2014

Academic Editor: Arie Zask

Copyright © 2014 Mohammed M. Ansari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Z. Kazimierczuk, M. Chalimoniuk, A. E. Laudy et al., “Synthesis and antimicrobial and nitric oxide synthase inhibitory activities of novel isothiourea derivatives,” Archives of Pharmacal Research, vol. 33, no. 6, pp. 821–830, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. E. G. Chalina and L. Chakarova, “Synthesis, hypotensive and antiarrhythmic activities of 3-alkyl-1-(2-hydroxy-5,8-dimethoxy-1,2,3,4-tetrahydro-3-naphthalenyl)ureas or thioureas and their guanidine analogues,” European Journal of Medicinal Chemistry, vol. 33, no. 12, pp. 975–983, 1998. View at Publisher · View at Google Scholar
  3. H. Stark, K. Purand, X. Ligneau et al., “Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activity,” Journal of Medicinal Chemistry, vol. 39, no. 5, pp. 1157–1163, 1996. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Walpole, S. Y. Ko, M. Brown et al., “2-Nitrophenylcarbamoyl-(S)-prolyl-(S)-3-(2-naphthyl)alanyl-N-benzyl-N- methylamide (SDZ NKT 343), a potent human NK1 tachykinin receptor antagonist with good oral analgesic activity in chronic pain models,” Journal of Medicinal Chemistry, vol. 41, no. 17, pp. 3159–3173, 1998. View at Publisher · View at Google Scholar · View at Scopus
  5. S. B. Tsogoeva, M. J. Hateley, D. A. Yalalov, K. Meindl, C. Weckbecker, and K. Huthmacher, “Thiourea-based non-nucleoside inhibitors of HIV reverse transcriptase as bifunctional organocatalysts in the asymmetric Strecker synthesis,” Bioorganic and Medicinal Chemistry, vol. 13, no. 19, pp. 5680–5685, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. F. Ruder and H. Kayser, “The thiourea insecticide diafenthiuron inhibits mitochondrial ATPase in vitro and in vivo by its carbodiimide product,” Biochemical Society Transactions, vol. 22, no. 1, pp. 241–244, 1994. View at Google Scholar · View at Scopus
  7. J. C. Kawalek, A. W. Andrews, and R. J. Pienta, “1-Naphthylthiourea: a mutagenic rodenticide that transforms hamster embryo cells,” Molecular Pharmacology, vol. 15, no. 3, pp. 678–684, 1979. View at Google Scholar · View at Scopus
  8. F. Z. El Aamrani, A. Kumar, J. L. Cortina, and A. M. Sastre, “Solvent extraction of copper(II) from chloride media using N-(thiocarbamoyl)benzamidine and N-benzoylthiourea derivatives,” Analytica Chimica Acta, vol. 382, no. 1-2, pp. 205–213, 1999. View at Publisher · View at Google Scholar · View at Scopus
  9. R. F. Bellina, US 4010199, 1977.
  10. G. Hermann, P. Hoffmann, and F. Rosendahl, “Dithiobiuret derivatives used for repelling birds, rodents, leporine animals and ruminants,” I. Ugi. US 3941887A, 1976.
  11. S. N. Pandeya, A. Kumar, B. N. Singh, and D. N. Mishra, “Synthesis and biological activity of isodithiobiurets, dithiobiurets, and dithiazoles,” Pharmaceutical Research, vol. 4, no. 4, pp. 321–326, 1987. View at Publisher · View at Google Scholar · View at Scopus
  12. J. E. Oliver, S. C. Chang, R. T. Braun, and A. B. Borkovic, “Insect chemosterilants. 10. Substituted dithiobiurets,” Journal of Medicinal Chemistry, vol. 14, pp. 772–773, 1971. View at Publisher · View at Google Scholar
  13. J. E. Oliver, R. T. Brown, R. L. Fye, and A. B. Borkovec, “Insect chemosterilants. 1,2,4-Dithiazolium salts and related compounds as additives to housefly diet,” Journal of Agricultural and Food Chemistry, vol. 21, no. 5, pp. 753–755, 1973. View at Publisher · View at Google Scholar
  14. F. Obrero and W. H. Pschnitzler, US 3741746, 1973.
  15. J. Zielinski and N. J. Kenilworth, “Use of dithiobiurets as fungicides,” U.S. Patent no. US3818104 A, 1974.
  16. N. Siddiqui and A. Husain, “Some substituted thiobiurets as possible analgesic agents,” Indian Journal of Pharmacology, vol. 33, no. 5, pp. 382–383, 2001. View at Google Scholar · View at Scopus
  17. N. Felföldi, M. Tóth, E. D. Chrysina, M.-D. Charavgi, K.-M. Alexacou, and L. Somsák, “Synthesis of new glycosyl biuret and urea derivatives as potential glycoenzyme inhibitors,” Carbohydrate Research, vol. 345, no. 2, pp. 208–213, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. A. S. Dandale and S. P. Deshmukh, “Synthesis and antimicrobial activity of N-lactosylated isothiobiurets,” Journal of the Indian Chemical Society, vol. 84, no. 12, pp. 1266–1268, 2007. View at Google Scholar · View at Scopus