Docking Studies and Biological Activity of Fosinopril Analogs

Table 1

Percent inhibition of ACE by Fosinopril and A1 at different concentrations.

Analog	Percent inhibition
	0.1 nM	0.2 nM	0.4 nM	0.6 nM	0.8 nM	1 nM
Fosinopril	44.07 ± 4.35	63.03 ± 6.01	68.72 ± 3.99	72.98 ± 4.76	88.15 ± 5.20	89.09 ± 3.82
A1	40.45 ± 3.60	50.20 ± 5.83	54.46 ± 7.14	60.04 ± 4.99	67.97 ± 3.84	76.25 ± 4.25