Research Article
Synthetic Antimicrobial Peptides Exhibit Two Different Binding Mechanisms to the Lipopolysaccharides Isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae
Figure 4
1H NMR spectra of (a) LPS isolated from P. aeruginosa; (b) AMP 70 in the presence of LPS isolated from P. aeruginosa; (c) AMP 79 in the presence of LPS isolated from P. aeruginosa. The chemical shift region from 6.0 to 0.0 ppm is shown. Addition of the AMP results in a reduction in peak intensities in the region 2.0 to 0.7 ppm. This region corresponds to the protons on the alkyl side chains of lipid A.
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