Design and Synthesis of Novel Antileishmanial Compounds

Scheme 4

Synthesis of four- and 10-carbon-atom-long unbranched derivatives (19 to 26). Reagents and conditions: (a) 1,4-dibromobutane or 1,10-dibromodecane, NaH, DMF (dry), 0–25^°C; (b) NaN₃, DMF (dry), 25^°C; (c) 1: NaN₃, PPh₃, 2: KOH, DMF (dry), 25^°C.