Design and Synthesis of Novel Antileishmanial Compounds

Scheme 6

Introduction of additional heterocyclic moieties to the assumed pharmacophore (compounds 29 and 30) for structure activity relationship investigations. Reagents and conditions: (a) imidazole, NaH, DMF, 25^°C; (b) potassium phthalimide, DMF (dry), 25^°C.