Table of Contents Author Guidelines Submit a Manuscript
International Journal of Medicinal Chemistry
Volume 2015 (2015), Article ID 430248, 54 pages
http://dx.doi.org/10.1155/2015/430248
Review Article

A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model

1Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, USA
2Department of Pharmacology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia
3Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS 39216, USA
4Department of Anesthesiology, Columbia University, New York, NY 10032, USA
5Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
6Milwaukee Institute of Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, USA

Received 11 February 2015; Revised 16 June 2015; Accepted 2 July 2015

Academic Editor: Hussein El-Subbagh

Copyright © 2015 Terry Clayton et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supporting information contains details on the construction of the Unified Pharmacophore/Receptor Model. In addition, the crystallographic data (excluding structure factors) for the structures in this report have been deposited with the Cambridge Crysallographic Data Centre as supplementary publication numbers 687205 (DMH-D-053), 222395 (XLi-093), and 222396 (DM-II-96). Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK, (fax +44-(0)1223-336033 or email: deposit@ccdc.cam.ac.uk). Structures of all compounds found within Tables 5-9 are also contained within the supporting information under Appendix III.

  1. Supplementary Material