Design and Synthesis of Pyrazole-3-one Derivatives as Hypoglycaemic Agents

Figure 8

Effect of metformin 120 mg/kg p.o. and 1, 2, 3, 4, 5, and 6 (40 mg/kg, p.o.) on blood glucose level. Values in parentheses indicate the dose in mg/kg. Data are expressed as mean ± SEM and analyzed by Bonferroni post hoc test, using two-way ANOVA, rats per group; , as compared to diabetic control, and as compared to normal.