In Silico Designing and Analysis of Inhibitors against Target Protein Identified through Host-Pathogen Protein Interactions in Malaria

Figure 8

Interaction of 5-(ethoxy[(piperidin-1-yl)amino]phosphoryl} oxy)-4-(hydroxymethyl)-2-(trifluoromethyl) benzene-1,3-diol with target protein at site II (a) and (b) docked molecule in the target protein at the site II with different colours showing different polarity and charges. Pink, blue, green, and cyan represent negative charge, positive charge and hydrophobic and polar residues, respectively. (c) LigPlot analysis of protein and ligand interactions.

(a)

(b)

(c)