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International Journal of Medicinal Chemistry
Volume 2016, Article ID 9346585, 8 pages
Research Article

Syntheses and Antibiotic Evaluation of 2-[(2R,4R)-4-Carboxy-2-hydroxypyrrolidin-1-yl]carbonylbenzene-1,5-dicarboxylic Acids and 2-Carbamoylbenzene-1,5-dicarboxylic Acid Analogues

1Department of Chemistry, Ahmadu Bello University, Zaria 810001, Nigeria
2School of Chemistry and Physics, University of KwaZulu-Natal, Private Bag X 54001, Durban 4000, South Africa

Received 27 October 2015; Accepted 16 December 2015

Academic Editor: Gangadhar B. Bagihalli

Copyright © 2016 Abdulrazaq Tukur et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The supplementary materials Appendix 1-78 shows the spectroscopy results for the synthesized compounds. Compound Z1 for example has its spectral data in Appendix 1-7, where Appendix 1 is the UV Spectrum, Appendix 2 is the 1H NMR spectrum, Appendix 3 is the 13C NMR spectrum, Appendix 4 is the DEPT-90, DEPT-135 and decouple 13C NMR Spectra combined. Appendix 5 shows the COSY spectrum, Appendix 6 is the HSQC spectrum and Appendix 7 is the NOESY spectrum. A similar arrangement is obtainable for the other compounds.

  1. Supplementary Material