Table of Contents
International Journal of Molecular Imaging
Volume 2011, Article ID 543267, 12 pages
http://dx.doi.org/10.1155/2011/543267
Review Article

SPECT Imaging Agents for Detecting Cerebral β-Amyloid Plaques

Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan

Received 29 July 2010; Revised 6 November 2010; Accepted 24 January 2011

Academic Editor: Alexander Drzezga

Copyright © 2011 Masahiro Ono and Hideo Saji. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [27 citations]

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  • James W. Scuffham, Matthew D. Wilson, Silvia Pani, Diana D. Duarte, Matthew C. Veale, Stephen Bell, Paul Seller, Paul J. Sellin, and Robert J. Cernik, “Evaluation of a new small-pixel CdTe spectroscopic detector in dual-tracer SPECT brain imaging,” 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC), pp. 3115–3118, . View at Publisher · View at Google Scholar
  • R. M. Koffie, C. T. Farrar, L.-J. Saidi, C. M. William, B. T. Hyman, and T. L. Spires-Jones, “Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging,” Proceedings of the National Academy of Sciences, vol. 108, no. 46, pp. 18837–18842, 2011. View at Publisher · View at Google Scholar
  • Marina Sagnou, Stamatia Tzanopoulou, Catherine P. Raptopoulou, Vassilis Psycharis, Henrik Braband, Roger Alberto, Ioannis C. Pirmettis, Minas Papadopoulos, and Maria Pelecanou, “A Phenylbenzothiazole Conjugate with the Tricarbonyl fac-[M(I)(CO)3]+ (M = Re, 99Tc, 99mTc) Core for Imaging of β-Amyloid Plaques,” European Journal of Inorganic Chemistry, vol. 2012, no. 27, pp. 4279–4286, 2012. View at Publisher · View at Google Scholar
  • Jiankang Zhang, Xingqin Zhou, and Xiaofeng Qin, “Preparation, quality control and physico-chemical properties of Tc-99m-BAT-AV-45,” Journal Of Radioanalytical And Nuclear Chemistry, vol. 292, no. 3, pp. 1377–1383, 2012. View at Publisher · View at Google Scholar
  • Kevin Cao, Mona Farahi, Marianna Dakanali, Willy M Chang, Christina J Sigurdson, Emmanuel A Theodorakis, and Jerry Yang, “Aminonaphthalene 2-cyanoacrylate (ANCA) probes fluorescently discriminate between amyloid-β and prion plaques in brain.,” Journal of the American Chemical Society, vol. 134, no. 42, pp. 17338–41, 2012. View at Publisher · View at Google Scholar
  • Yosef Koronyo, Brenda C. Salumbides, Keith L. Black, and Maya Koronyo-Hamaoui, “Alzheimer's Disease in the Retina: Imaging Retinal A beta Plaques for Early Diagnosis and Therapy Assessment,” Neurodegenerative Diseases, vol. 10, no. 1-4, pp. 285–293, 2012. View at Publisher · View at Google Scholar
  • Masahiro Ono, Yan Cheng, Hiroyuki Kimura, Hiroyuki Watanabe, Kenji Matsumura, Masashi Yoshimura, Shimpei Iikuni, Yoko Okamoto, Masafumi Ihara, Ryosuke Takahashi, and Hideo Saji, “Development of Novel I-123-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of beta-Amyloid Plaques in Alzheimer's Disease,” Plos One, vol. 8, no. 9, 2013. View at Publisher · View at Google Scholar
  • Hadas Skaat, Enav Corem-Slakmon, Igor Grinberg, David Last, David Goez, Yael Mardor, and Shlomo Margel, “Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-beta fibrils,” International Journal of Nanomedicine, vol. 8, pp. 4063–4076, 2013. View at Publisher · View at Google Scholar
  • Arshdeep Sidhu, Ine Segers-Nolten, and Vinod Subramaniam, “Solution conditions define morphological homogeneity of α-Synuclein fibrils,” Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2014. View at Publisher · View at Google Scholar
  • Hiroyuki Watanabe, Masahiro Ono, Shimpei Iikuni, Masashi Yoshimura, Kenji Matsumura, Hiroyuki Kimura, and Hideo Saji, “A 68Ga Complex Based on Benzofuran Scaffold for the Detection of β-Amyloid Plaques,” Bioorganic & Medicinal Chemistry Letters, 2014. View at Publisher · View at Google Scholar
  • Zijing Li, Mengchao Cui, Jinming Zhang, Jiapei Dai, Xiaojun Zhang, Peng Chen, Hongmei Jia, and Boli Liu, “Novel 18F-Labeled dibenzylideneacetone derivatives as potential positron emission tomography probes for In vivo imaging of β-amyloid plaques,” European Journal of Medicinal Chemistry, 2014. View at Publisher · View at Google Scholar
  • Kanchan Chauhan, Anupama Datta, Anupriya Adhikari, Krishna Chuttani, Ajai Kumar Singh, and Anil K. Mishra, “ 68 Ga based probe for Alzheimer's disease: synthesis and preclinical evaluation of homodimeric chalcone in β-amyloid imaging ,” Organic & Biomolecular Chemistry, vol. 12, no. 37, pp. 7328, 2014. View at Publisher · View at Google Scholar
  • Pravin Ambure, and Kunal Roy, “Advances in quantitative structure–activity relationship models of anti-Alzheimer’s agents,” Expert Opinion on Drug Discovery, pp. 1–27, 2014. View at Publisher · View at Google Scholar
  • Hiroyuki Watanabe, Masahiro Ono, Shimpei Iikuni, Hiroyuki Kimura, Yoko Okamoto, Masafumi Ihara, and Hideo Saji, “ Synthesis and biological evaluation of 123 I-labeled pyridyl benzoxazole derivatives: novel β-amyloid imaging probes for single-photon emission computed tomography ,” RSC Adv., vol. 5, no. 2, pp. 1009–1015, 2014. View at Publisher · View at Google Scholar
  • Viviane L. Ndam Ngoungoure, Jan Schluesener, Paul F. Moundipa, and Hermann Schluesener, “Natural polyphenols binding to amyloid: A broad class of compounds to treat different human amyloid diseases,” Molecular Nutrition & Food Research, 2014. View at Publisher · View at Google Scholar
  • David J. Hayne, SinChun Lim, and Paul S. Donnelly, “Metal complexes designed to bind to amyloid-beta for the diagnosis and treatment of Alzheimer's disease,” Chemical Society Reviews, vol. 43, no. 19, pp. 6701–6715, 2014. View at Publisher · View at Google Scholar
  • Dominique Garin, Angélique Virgone-Carlotta, Bülent Gözel, Fatima Oukhatar, Pascale Perret, Danièle Marti-Battle, Monique Touret, Philippe Millet, Michel Dubois-Dauphin, David Meyronet, Nathalie Streichenberger, Frank M. Laferla, Martine Demeunynck, Sabine Chierici, Marcelle Moulin Sallanon, and Catherine Ghezzi, “COB231 targets amyloid plaques in post-mortem human brain tissue and in an Alzheimer mouse model,” Journal of Neurochemistry, 2015. View at Publisher · View at Google Scholar
  • Killian Oukoloff, Monika Cieslikiewicz-Bouet, Sovy Chao, Emilie Da Costa Bran-quinho, Cedric Bouteiller, Ludovic Jean, and Pierre-Yves Renard, “PET and SPECT Radiotracers for Alzheimer's Disease,” Current Medicinal Chemistry, vol. 22, no. 28, pp. 3278–3304, 2015. View at Publisher · View at Google Scholar
  • Kaixiang Zhou, Hualong Fu, Liang Feng, Mengchao Cui, Jiapei Dai, and Boli Liu, “The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques,” Chem. Commun., vol. 51, no. 58, pp. 11665–11668, 2015. View at Publisher · View at Google Scholar
  • Nadav J. Hart, Yosef Koronyo, Keith L. Black, and Maya Koronyo-Hamaoui, “Ocular indicators of Alzheimer’s: exploring disease in the retina,” Acta Neuropathologica, 2016. View at Publisher · View at Google Scholar
  • Douglas R. Rice, Kasey J. Clear, and Bradley D. Smith, “ Imaging and therapeutic applications of zinc( ii )-dipicolylamine molecular probes for anionic biomembranes ,” Chem. Commun., 2016. View at Publisher · View at Google Scholar
  • S. Chaturvedi, A. Kaul, Puja P. Hazari, and Anil K. Mishra, “Mapping neuroreceptors with metal-labeled radiopharmaceuticals,” Med. Chem. Commun., 2017. View at Publisher · View at Google Scholar
  • José C. J. M. D. S. Menezes, “Arylidene indanone scaffold: medicinal chemistry and structure–activity relationship view,” RSC Adv., vol. 7, no. 15, pp. 9357–9372, 2017. View at Publisher · View at Google Scholar
  • M.L. Bolognesi, “From Imaging Agents to Theranostic Drugs in Alzheimer's Disease,” Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2017. View at Publisher · View at Google Scholar
  • Sho Kaide, Masahiro Ono, Hiroyuki Watanabe, Yoichi Shimizu, Yuji Nakamoto, Kaori Togashi, Aiko Yamaguchi, Hirofumi Hanaoka, and Hideo Saji, “Conversion of Iodine to Fluorine-18 Based on Iodinated Chalcone and Evaluation for β-Amyloid PET Imaging,” Bioorganic & Medicinal Chemistry, 2018. View at Publisher · View at Google Scholar
  • Sho Kaide, Masahiro Ono, Hiroyuki Watanabe, Ayane Kitada, Masashi Yoshimura, Yoichi Shimizu, Masafumi Ihara, and Hideo Saji, “Structure–Activity Relationships of Radioiodinated Benzoimidazopyridine Derivatives for Detection of Tau Pathology,” ACS Medicinal Chemistry Letters, 2018. View at Publisher · View at Google Scholar
  • Kanchan Chauhan, Anjani K. Tiwari, Nidhi Chadha, Ankur Kaul, Ajai Kumar Singh, and Anupama Datta, “ Chalcone Based Homodimeric PET Agent, 11 C-(Chal) 2 DEA-Me, for Beta Amyloid Imaging: Synthesis and Bioevaluation ,” Molecular Pharmaceutics, 2018. View at Publisher · View at Google Scholar