CA19-9 as a Potential Target for Radiolabeled Antibody-Based Positron Emission Tomography of Pancreas Cancer
In vitro functional characterization of the anti-CA19-9 intact murine antibody. (a) Equilibrium binding affinity constant as determined by cell-based ELISA of the anti-CA19-9 antibody. (b) Flow cytometry showing binding specificity of the anti-CA19-9 antibody to each human cancer cell line. Red line represents cells only. Blue line represents cells incubated with only PE-conjugated goat antimouse antibody. Green line represents cells incubated with intact mouse anti-CA19-9 antibody and PE-conjugated goat antimouse antibody.