Quantitative Longitudinal Imaging of Vascular Inflammation and Treatment by Ezetimibe in apoE Mice by FMT Using New Optical Imaging Biomarkers of Cathepsin Activity and 𝜶_𝑣𝜷_𝟑 Integrin

Figure 2

Examples of in vivo FMT images of apoE^−/− mice and ex vivo fluorescence images of the corresponding areas of dissected arteries and correlation between the in vivo and ex vivo measurements. (a), (b) ProSense (𝑟=0.89, 𝑃<0.05); (c), (d) IntegriSense (𝑟=0.86, 𝑃<0.05). (e), (f) Cat B FAST (𝑟=0.94, 𝑃<0.05). Plots for ProSense and IntegriSense are based on seven and for Cat B FAST on six different animals.

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