Feasibility Evaluation of Radioimmunoguided Surgery of Breast Cancer

Table 2

Minimum T:B ± standard deviation to achieve tumour edge delineation. Background activity concentration is a surrogate for administered activity and can be related to relative error in GDP measurements. The combinations of parameters resulting in the optimum overall performance and used to generate the data in this table are as follows: for ¹¹¹In, a 100 keV energy-window threshold and a 0.5 mm collimator length; for ^99mTc, a 90 keV energy-window threshold and 0.0 cm collimation; and for ¹³¹I, a 150 keV energy-window threshold and 0.0 cm collimation.

Radionuclide	Background activity concentration
	1 kBq/mL	2 kBq/mL	3 kBq/mL	4 kBq/mL	5 kBq/mL
^99mTc	14.4±1.1	10.0±0.8	8.1±0.6	7.0±0.5	6.2±0.5
^111In	11.9±0.9	8.3±0.7	6.7±0.6	6.0±0.6	5.2±0.4
^131I	28.3±2.2	19.4±1.5	15.6±1.2	13.4±1.0	12.0±0.9