Table of Contents
International Journal of Palliative Care
Volume 2014, Article ID 214265, 7 pages
http://dx.doi.org/10.1155/2014/214265
Research Article

Incidence and Cause of Delirium in Hospitalized Patients between the Ages of 18 and 56: A Retrospective Chart Review

1Department of Family Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242-1000, USA
2Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242-1000, USA
3Brookdale Department of Geriatrics and Palliative Medicine, Mount Sinai School of Medicine, New York, NY 10029-6574, USA
4Geriatric Research, Education and Clinical Center, James J. Peters VA Medical Center, Bronx, NY 10468, USA

Received 20 June 2013; Accepted 11 November 2013; Published 28 January 2014

Academic Editors: Sushma Bhatnagar, Seref Komurcu, and Simon Noble

Copyright © 2014 Michelle T. Weckmann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. G. Lawlor, B. Gagnon, I. L. Mancini et al., “Occurrence, causes, and outcome of delirium in patients with advanced cancer: a prospective study,” Archives of Internal Medicine, vol. 160, no. 6, pp. 786–794, 2000. View at Google Scholar · View at Scopus
  2. V. Ljubisavljevic and B. Kelly, “Risk factors for development of delirium among oncology patients,” General Hospital Psychiatry, vol. 25, no. 5, pp. 345–352, 2003. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Z. Cohen, E. A. Pace, G. Kaur, and E. Bruera, “Delirium in advanced cancer leading to distress in patients and family caregivers,” Journal of Palliative Care, vol. 25, no. 3, pp. 164–171, 2009. View at Google Scholar · View at Scopus
  4. C. Centeno, Á. Sanz, and E. Bruera, “Delirium in advanced cancer patients,” Palliative Medicine, vol. 18, no. 3, pp. 184–194, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Leonard, J. Spiller, J. Keen, A. MacLullich, B. Kamholtz, and D. Meagher, “Symptoms of depression and delirium assessed serially in palliative-care inpatients,” Psychosomatics, vol. 50, no. 5, pp. 506–514, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. J. R. Fann, C. M. Alfano, S. Roth-Roemer, W. J. Katon, and K. L. Syrjala, “Impact of delirium on cognition, distress, and health-related quality of life after hematopoietic stem-cell transplantation,” Journal of Clinical Oncology, vol. 25, no. 10, pp. 1223–1231, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Morita, Y. Tei, and S. Inoue, “Impaired communication capacity and agitated delirium in the final week of terminally ill cancer patients: prevalence and identification of research focus,” Journal of Pain and Symptom Management, vol. 26, no. 3, pp. 827–834, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Leonard, B. Raju, M. Conroy et al., “Reversibility of delirium in terminally ill patients and predictors of mortality,” Palliative Medicine, vol. 22, no. 7, pp. 848–854, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. M. González, G. Martínez, J. Calderón et al., “Impact of delirium on short-term mortality in elderly inpatients: a prospective cohort study,” Psychosomatics, vol. 50, no. 3, pp. 234–238, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. D. K. Kiely, E. R. Marcantonio, S. K. Inouye et al., “Persistent delirium predicts greater mortality,” Journal of the American Geriatrics Society, vol. 57, no. 1, pp. 55–61, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Witlox, L. S. M. Eurelings, J. F. M. De Jonghe, K. J. Kalisvaart, P. Eikelenboom, and W. A. van Gool, “Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis,” The Journal of the American Medical Association, vol. 304, no. 4, pp. 443–451, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. R. Basinski, C. M. Alfano, W. J. Katon, K. L. Syrjala, and J. R. Fann, “Impact of delirium on distress, health-related quality of life, and cognition 6 months and 1 year after hematopoietic cell transplant,” Biology of Blood and Marrow Transplantation, vol. 16, no. 6, pp. 824–831, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. D. S. Davydow, “Symptoms of depression and anxiety after delirium,” Psychosomatics, vol. 50, no. 4, pp. 309–316, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. C.-K. Fang, H.-W. Chen, S.-I. Liu, C.-J. Lin, L.-Y. Tsai, and Y.-L. Lai, “Prevalence, detection and treatment of delirium in terminal cancer inpatients: a prospective survey,” Japanese Journal of Clinical Oncology, vol. 38, no. 1, pp. 56–63, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Wada, M. Wada, M. Wada, and H. Onishi, “Characteristics, interventions, and outcomes of misdiagnosed delirium in cancer patients,” Palliative and Supportive Care, vol. 8, no. 2, pp. 125–131, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. L. J. Beglinger, J. A. Mills, S. M. Vik et al., “The neuropsychological course of acute delirium in adult hematopoietic stem cell transplantation patients,” Archives of Clinical Neuropsychology, vol. 26, no. 2, pp. 98–107, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. J. R. Fann, R. A. Hubbard, C. M. Alfano, S. Roth-Roemer, W. J. Katon, and K. L. Syrjala, “Pre- and post-transplantation risk factors for delirium onset and severity in patients undergoing hematopoietic stem-cell transplantation,” Journal of Clinical Oncology, vol. 29, no. 7, pp. 895–901, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Sagawa, T. Akechi, T. Okuyama, M. Uchida, and T. A. Furukawa, “Etiologies of delirium and their relationship to reversibility and motor subtype in cancer patients,” Japanese Journal of Clinical Oncology, vol. 39, no. 3, pp. 175–182, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. J.-D. Gaudreau, P. Gagnon, F. Harel, M.-A. Roy, and A. Tremblay, “Psychoactive medications and risk of delirium in hospitalized cancer patients,” Journal of Clinical Oncology, vol. 23, no. 27, pp. 6712–6718, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. W. Breitbart, C. Gibson, and A. Tremblay, “The delirium experience: delirium recall and delirium-related distress in hospitalized patients with cancer, their spouses/caregivers, and their nurses,” Psychosomatics, vol. 43, no. 3, pp. 183–194, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. P. G. Lawlor, R. L. Fainsinger, and E. D. Bruera, “Delirium at the end of life: critical issues in clinical practice and research,” The Journal of the American Medical Association, vol. 284, no. 19, pp. 2427–2429, 2000. View at Google Scholar · View at Scopus
  22. E. Bruera, S. H. Bush, J. Willey et al., “Impact of Delirium and recall on the level or distress in patients with advanced cancer and their family caregivers,” Cancer, vol. 115, no. 9, pp. 2004–2012, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. C. Brauer, R. S. Morrison, S. B. Silberzweig, and A. L. Siu, “The cause of delirium in patients with hip fracture,” Archives of Internal Medicine, vol. 160, no. 12, pp. 1856–1860, 2000. View at Google Scholar · View at Scopus
  24. S. K. Inouye, L. Leo-Summers, Y. Zhang, S. T. Bogardus Jr., D. L. Leslie, and J. V. Agostini, “A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method,” Journal of the American Geriatrics Society, vol. 53, no. 2, pp. 312–318, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. “What is advanced cancer,” 2012, http://www.cancer.org/.
  26. K. J. Neufeld, M. J. Hayat, J. M. Coughlin et al., “Evaluation of two intensive care delirium screening tools for non-critically ill hospitalized patients,” Psychosomatics, vol. 52, no. 2, pp. 133–140, 2011. View at Google Scholar
  27. J. A. Spiller and J. C. Keen, “Hypoactive delirium: assessing the extent of the problem for inpatient specialist palliative care,” Palliative Medicine, vol. 20, no. 1, pp. 17–23, 2006. View at Publisher · View at Google Scholar · View at Scopus