Ghrelin: Central Nervous System Sites of Action in Regulation of Energy Balance
Figure 1
Ghrelin modulates the electrical activity of SFO neurons. (a) Nissl-stained coronal section showing the SFO. (b) Representative current-clamp recordings from dissociated SFO neurons that were depolarized by application of 10 nM ghrelin. This effect is mediated by activation of a cation conductance. Interestingly, separate populations of SFO neurons depolarize in response to either ghrelin or amylin (not shown). No SFO neurons are sensitive to both ghrelin and amylin; see [45].
