Use of Ghrelin as a Treatment for Inflammatory Bowel Disease: Mechanistic Considerations

Table 1

Levels of acyl and total ghrelin among IBD subjects and healthy controls.

	Healthy controls	CD, active	CD, remission	UC, active	UC, remission	IBD, active	IBD,; remission
Acyl ghrelin
Ates et al. 2008 [51]	84±14	110±10 ***	75±15	108±11 ***	71±13
Karmiris et al. 2006 [52]	14.8±3.0	49.4±4.2^###		48.2±4.2^###
Total ghrelin
Peracchi et al. 2006 [53]	203±81.1					323.6±119.2^∗∗∗,###	217.4±64.9
Nishi et al. 2005 [54]		220.6±98.8 NS	202.3±86.4
Alexandridis et al. 2009 [55]						402.4±462.6	148.2±59.6 *

Statistical significance: active disease versus remission: *𝑃<0.05, ***𝑃<0.001; active disease versus controls: ^###𝑃<0.001; NS: not significant.