Applications of Propargyl Esters of Amino Acids in Solution-Phase Peptide Synthesis

Table 2

Preparation of propargyl esters of amino acids.

Entry	Amino acid	Amino propargyl ester	Yield^a (%)
1	H-Ala-OH		72
2	H-Gly-OH		69
3	H-leu-OH		76
4	H-Pro-OH		71
5	H-Ser-OH		70
6	H-Phe-OH		76
7	H-Glu-OH		62
8	H-Thr-OH		69
9	4-ABA		88
10	3-ABA		90

^aThe yields reported are of pure compounds isolated after multiple washings with diethyl ether.