Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat

Figure 2

Tat peptide has no effect on reporter cell viability. P4-R5 MAGI cells were exposed to half log concentrations of Tat peptide for 2 h, washed, and assessed immediately for changes in cell viability or after extended maintenance (24 h or 48 h after exposure) in the absence of Tat peptide. Percent changes in cell viability were calculated relative to mock-exposed cells. The graph represents data from two independent assays in which exposure to each concentration of peptide was repeated in quadruplicate. Error bars represent standard deviations.